Hotels in San Francisco, Panama City

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for San Francisco hotels

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,001 reviews)
"Everything was great, really nice stay"
United States
Hary
The price is CA $183
CA $201 total
includes taxes & fees
May 16 - May 17
Sheraton Grand Panama

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
2.5 star property
San Francisco
7.4 out of 10, Good, (9 reviews)
"Amazing! Great staff and wonderful high top views. "
United States
Krysta Alicia
The price is CA $175
CA $193 total
includes taxes & fees
May 3 - May 4
Dovle Residences by HMS-Preferred Member

Cozy Urban Loft 1br Near Coast

Cozy Urban Loft 1br Near Coast
2.0 star property
San Francisco
The price is CA $223
CA $292 total
includes taxes & fees
May 2 - May 3
Cozy Urban Loft 1br Near Coast

Serenade Lodging Rooms

Serenade Lodging Rooms
3.0 star property
San Francisco
8.6 out of 10, Excellent, (24 reviews)
"Nice affordable place. "
United States
Sandor
The price is CA $72
CA $80 total
includes taxes & fees
Apr 29 - Apr 30
Serenade Lodging Rooms

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
The price is CA $62
CA $278 total
includes taxes & fees
May 14 - May 15
Living 73 Panamá by Boutique Apartments

Aloft Panama

Aloft Panama
3.5 star property
San Francisco
8.8 out of 10, Excellent, (1,006 reviews)
"Good hotel, good dining options. "
United States
Rebecca
The price is CA $169
CA $186 total
includes taxes & fees
May 11 - May 12
Aloft Panama

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,175 reviews)
"Clean room, very helpful staff and great breakfast."
United States
Emmanuela
The price is CA $139
CA $153 total
includes taxes & fees
Apr 30 - May 1
Ramada Plaza by Wyndham Panama Punta Pacifica

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.4 out of 10, Good, (189 reviews)
"Nice place, convenient and nicely priced"
United States
Camille L
The price is CA $67
CA $265 total
includes taxes & fees
Apr 29 - Apr 30
Boutique Apartments Panamá Coco del Mar

Casa Orquídea

Casa Orquídea
2.0 star property
San Francisco
7.4 out of 10, Good, (11 reviews)
"Super nice house"
United States
SANTIAGO
The price is CA $82
CA $92 total
includes taxes & fees
Apr 29 - Apr 30
Casa Orquídea

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,142 reviews)
"After trying out other hotels, this is the best all around value, everything was wonderful even the restaurant "
Canada
Beverly
The price is CA $141
CA $155 total
includes taxes & fees
May 8 - May 9
Plaza Paitilla Inn Hotel

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,004 reviews)
"Very nice and safe place to stay"
United States
Nilesh
The price is CA $369
CA $406 total
includes taxes & fees
May 29 - May 30
JW Marriott Panama

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,000 reviews)
"Breakfast was great and Shops being nearby was fantastic, especially for my daughter"
United States
Christopher
The price is CA $161
CA $177 total
includes taxes & fees
May 10 - May 11
Courtyard by Marriott Panama Multiplaza Mall

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,652 reviews)
"Great location, breakfast was good, staff really helpful."
United States
Victor
The price is CA $145
CA $160 total
includes taxes & fees
May 27 - May 28
Decapolis Hotel Panama City

w Bright 1BR w Private Balcony in San Francisco

w Bright 1BR w Private Balcony in San Francisco
2.0 star property
San Francisco
The price is CA $150
CA $209 total
includes taxes & fees
Apr 29 - Apr 30
w Bright 1BR w Private Balcony in San Francisco

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,006 reviews)
"Stayed a week, loved it!"
United States
Leon Aaron
The price is CA $195
CA $215 total
includes taxes & fees
May 3 - May 4
Las Americas Golden Tower Panama

Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
7.8 out of 10, Good, (38 reviews)
"The couch is a little worn and possibly need to be replaced but other than that this place was excellent"
United States
Clifton
The price is CA $45
CA $198 total
includes taxes & fees
May 3 - May 4
Boutique Apartments Atlapa

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very good, (1,523 reviews)
"Nice stay"
United States
Diego
The price is CA $254
CA $283 total
includes taxes & fees
May 3 - May 4
Megapolis Hotel Panamá

Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (3 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is CA $201
CA $430 total
includes taxes & fees
May 28 - May 29
Wanders Panama by Boutique Apartments

Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.2 out of 10, Wonderful, (602 reviews)
"Nice place would stay again"
United States
Andres
The price is CA $265
CA $292 total
includes taxes & fees
May 18 - May 19
Residence Inn by Marriott Panama City

Feel Like Home in Spacious 1br Apartment

Feel Like Home in Spacious 1br Apartment
2.0 star property
San Francisco
The price is CA $223
CA $292 total
includes taxes & fees
Apr 29 - Apr 30
Feel Like Home in Spacious 1br Apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in San Francisco

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Breakfast, lunch, dinner served; international cuisine
Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
9.6
Exceptional
1,175 reviews
View
Terrace/patio
Plaza Paitilla Inn Hotel
3.5 star property
9.4
Exceptional
2,142 reviews
View
Daily buffet breakfast (PAB 21 per person)
Sheraton Grand Panama
4.0 star property
8.6
Excellent
1,001 reviews
View
View from property
Las Americas Golden Tower Panama
4.0 star property
9.0
Wonderful
1,006 reviews
View
Front of property
Megapolis Hotel Panamá
4.5 star property
8.4
Very good
1,523 reviews
View

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about San Francisco
Learn more about San Francisco

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Felipe

If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.

Calidonia

You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

Top San Francisco Hotel Reviews

Frequently asked questions

What are the best hotels in San Francisco that travellers recommend?
Two of the best hotels in San Francisco that receive consistently high recommendations from travellers are the JW Marriott Panama and the Ramada Plaza by Wyndham Panama Punta Pacifica.

The 5-star JW Marriott Panama, with an excellent 9.0 rating, is praised by guests for its beautiful and amazing rooms, as well as its friendly and amazing staff. The hotel offers luxurious amenities such as 24-hour room service, designer toiletries, and Egyptian cotton sheets. It is conveniently located near Avenida Balboa, 1.0 km away, and Multicentro Panama, 1.1 km away.

Another highly recommended option is the 4-star Ramada Plaza by Wyndham Panama Punta Pacifica, which boasts an outstanding 9.6 rating. Guests consistently highlight the friendly and helpful staff, the spacious and clean rooms, and the convenient location. The hotel is situated in a shopping district, with a shopping mall on-site, offering easy access for retail therapy.
What are the best family hotels in San Francisco?
For family-friendly hotels in San Francisco, you have several excellent options, including the JW Marriott Panama, the Ramada Plaza by Wyndham Panama Punta Pacifica, and the Sheraton Grand Panama.

The 5-star JW Marriott Panama, with a 9.0 rating, is a superb choice for families. It offers sofa beds, free cribs, and a children's pool, along with connecting rooms for added convenience. Guests frequently praise the amazing staff and beautiful rooms, and the hotel's central location is excellent, being just 1.0 km from Avenida Balboa and 1.2 km from Multiplaza Pacific Mall.

Another highly-rated option is the 4-star Ramada Plaza by Wyndham Panama Punta Pacifica, boasting an impressive 9.6 rating. This hotel provides child-friendly window designs, free rollaway extra beds, a pool, and kids' meals. Guests consistently highlight the friendly and helpful staff, the spacious and clean rooms, and the convenient location. The breakfast, including the buffet, also receives great reviews.

The 4-star Sheraton Grand Panama, rated 8.6, is also an excellent family hotel. It features kids' meals, sofa beds, a pool, free cribs, and connecting rooms. There is also a playground for children. The hotel is well-located, being 1.1 km from Multiplaza Pacific Mall and 1.4 km from Omar Torrijos Recreational Park. Guests appreciate the nice, quiet rooms, friendly staff, and excellent amenities.

Other good choices include the 4.5-star Megapolis Hotel Panamá, with an 8.4 rating, which offers free cribs, rollaway extra beds, and is conveniently connected to a shopping mall. The 3.5-star Aloft Panama, rated 8.6, also provides free cribs, rollaway extra beds, and a pool.
What are the best 5-star hotels in San Francisco?
For a highly-rated 5-star hotel in San Francisco, the JW Marriott Panama is an excellent choice.

This 5-star hotel, with a 9.0 rating, consistently receives praise for its friendly and amazing staff, beautiful rooms, and excellent amenities. Guests particularly appreciate the luxury touches such as Egyptian cotton sheets and premium bedding, ensuring a comfortable stay. The hotel also features a poolside bar and a restaurant with poolside service, along with 24-hour room service and valet parking for added convenience. Designer toiletries are also provided. The JW Marriott Panama is exceptionally well-located, being just 1.0 km from Avenida Balboa, 1.1 km from Multicentro Panama, and 1.2 km from Multiplaza Pacific Mall.
What are the best spa hotels in San Francisco?
For excellent spa hotels in San Francisco, consider the Decapolis Hotel Panama City and the Megapolis Hotel Panamá.

The 4-star Decapolis Hotel Panama City, with an 8.6 rating, offers an extensive full-service spa. Guests can enjoy a wide range of treatments including manicures, pedicures, body scrubs, aromatherapy, deep tissue massages, and facials. The spa also features a steam room and hot tub for ultimate relaxation. This hotel is also very conveniently located near Avenida Balboa.

Another superb choice is the 4.5-star Megapolis Hotel Panamá, rated 8.4. Its full-service spa provides an array of options such as Swedish and hot stone massages, hydrotherapy, and Ayurvedic treatments. There are also couples' treatment rooms and a Turkish bath, ensuring a truly indulgent experience. Like the Decapolis, it is also close to Avenida Balboa.
Which beach resorts in San Francisco do travellers love?
In San Francisco, travellers consistently recommend the Sheraton Grand Panama.

The 4-star Sheraton Grand Panama, with an excellent 8.6 rating, is a popular choice for its convenient location and extensive amenities. Guests frequently praise the nice and quiet rooms, friendly and great staff, and the excellent amenities and venue. The hotel also boasts a full-service spa with a steam room, Turkish bath, and various treatments, great for relaxation. For those interested in shopping, it offers onsite shopping, designer stores, and a shuttle to a shopping centre, with Multiplaza Pacific Mall just 1.1 km away.
What hotels in San Francisco offer free breakfast?
Several excellent hotels in San Francisco, Panama, offer complimentary breakfast, including the Ramada Plaza by Wyndham Panama Punta Pacifica, Plaza Paitilla Inn Hotel, Residence Inn by Marriott Panama City, Decapolis Hotel Panama City, and Megapolis Hotel Panamá.

The 4-star Ramada Plaza by Wyndham Panama Punta Pacifica, with an impressive 9.6 rating, offers a fantastic free buffet breakfast. Guests consistently praise the spacious and clean rooms, as well as the friendly and helpful staff. The hotel also features onsite shopping, making it very convenient.

Another great option is the 3.5-star Plaza Paitilla Inn Hotel, rated 9.4. This hotel provides a fabulous free buffet breakfast and free self-parking. Its location is excellent, just 0.5 km from Avenida Balboa and 1.1 km from Uruguay Street.

The 4-star Residence Inn by Marriott Panama City, with a 9.0 rating, provides a free continental and self-serve breakfast. Guests appreciate the fantastic, big rooms and the excellent, friendly staff. The hotel also offers a 24-hour airport shuttle and free WiFi.

The 4-star Decapolis Hotel Panama City, rated 8.6, offers a good free buffet breakfast. This hotel also boasts a full-service spa with a wide range of treatments, including massages, facials, and a steam room. It is conveniently located just 0.1 km from Avenida Balboa.

Finally, the 4.5-star Megapolis Hotel Panamá, with an 8.4 rating, also provides a great free buffet breakfast. Guests often praise the clean, amazing rooms and the exceptional customer service. The hotel features an extensive spa offering various massages and body treatments.
What are the top pet-friendly hotels in San Francisco?
For top pet-friendly hotels in San Francisco, consider the Residence Inn by Marriott Panama City, the Sheraton Grand Panama, and the Courtyard by Marriott Panama Multiplaza Mall.

The 4-star Residence Inn by Marriott Panama City, with a 9.0 rating, is a fantastic choice for pet owners, offering permitted pet stays and complimentary breakfast. Guests frequently mention the spacious rooms and convenient location, being just 0.5 km from Avenida Balboa and 0.7 km from Multicentro Panama.

Another excellent option is the 4-star Sheraton Grand Panama, rated 8.6, which welcomes pets and provides food and water bowls. This hotel features on-site shopping, including designer stores, and offers a shuttle to the shopping centre. It is located near Multiplaza Pacific Mall, just 1.1 km away.

The 4-star Courtyard by Marriott Panama Multiplaza Mall, with an 8.8 rating, also permits pets, including both dogs and cats. This hotel is integrated with the Multiplaza Pacific Mall, placing designer stores and other shopping amenities right on your doorstep.
What are the top boutique hotels in San Francisco?
For top boutique hotels in San Francisco, consider the Sheraton Grand Panama or the Ramada Plaza by Wyndham Panama Punta Pacifica.

The 4-star Sheraton Grand Panama, with an 8.6 rating, is an excellent choice for its convenient location and on-site shopping. Guests frequently praise its nice, quiet rooms and the friendly, great staff. It features a full-service spa with various treatments, including couples treatment rooms, and is located near the Multiplaza Pacific Mall and Avenida Balboa.

Another highly-rated option is the 4-star Ramada Plaza by Wyndham Panama Punta Pacifica, which boasts an impressive 9.6 rating. This hotel is praised for its friendly, helpful staff and spacious, clean rooms. Its convenient location and on-site shopping mall are significant advantages. Guests particularly enjoy the excellent breakfast buffet.
What are the best budget hotels in San Francisco?
For a highly-rated budget hotel in San Francisco, consider the ESHEL SUITES PANAMA.

The ESHEL SUITES PANAMA, with an exceptional 10.0 rating, offers a fantastic experience for budget-conscious travellers. Guests particularly appreciate the complimentary 24-hour airport shuttle service, making arrivals and departures seamless. The hotel also provides free Wi-Fi and wired internet in public areas, along with a free grocery shopping service. For those interested in shopping, the hotel has designer stores on-site and is conveniently located near other outlets and a shopping district. It is also well-situated for exploring, with Avenida Balboa just 0.6 km away and the National Shrine of the Heart of Mary 1.6 km distant.
What are the most romantic hotels in San Francisco for couples?
For a romantic stay in San Francisco for couples, consider the JW Marriott Panama or the Decapolis Hotel Panama City.

The 5-star JW Marriott Panama, with a 9.0 rating, offers luxurious suites and a delightful poolside bar, great for enjoying a quiet drink together. Guests frequently praise the beautiful rooms and excellent amenities. It is also conveniently located just 1 km from Avenida Balboa and 1.2 km from Multiplaza Pacific Mall.

Another excellent choice for couples is the 4-star Decapolis Hotel Panama City, rated 8.6. This hotel boasts an extensive spa with couples' treatment rooms, a hot tub, and various massage options, providing a relaxing experience for two. Many rooms offer sea or ocean views, and guests often comment on the friendly staff and good breakfast. It is also very close to Avenida Balboa, just 0.1 km away.
What are the best hotels in San Francisco near Avenida Balboa?
For hotels in San Francisco near Avenida Balboa, consider ESHEL SUITES PANAMA and Stunning City Center.

ESHEL SUITES PANAMA, with a superb 10.0 rating, is conveniently located just 0.6 km from Avenida Balboa. This property offers free rollaway extra beds and cribs, making it very suitable for families. Guests can also benefit from a free grocery shopping service and enjoy the convenience of onsite designer stores and a grocery or convenience store.

Another excellent option is the 3.5-star Stunning City Center, rated 9.0. It is 2.0 km from Avenida Balboa and provides an outdoor pool and free self-parking. Families will appreciate the availability of highchairs for children and free WiFi.
When is the best time to go to San Francisco?
The best time to visit San Francisco, Panama, is during the dry season, which typically runs from December to April.

During these months, you'll experience consistently sunny days and lower humidity, making it ideal for exploring the city and enjoying outdoor activities. Temperatures are pleasantly warm, usually ranging from 25°C to 32°C. This period is great for those looking to avoid the heavier rainfall and higher humidity of the wet season.

For travellers who prefer slightly fewer crowds and don't mind the occasional shower, the shoulder months of May and November can also be a good option. The rain usually comes in short, heavy bursts, often in the afternoon, leaving plenty of time for sightseeing.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right San Francisco hotel for you.
How can I save on a San Francisco hotel booking with Expedia?
With Expedia, you'll unlock our lowest prices by becoming a member. It's free and easy to join, and you can even access member perks too. Just remember to sign in to get our best prices on San Francisco hotels. Another way to save is by booking your hotel and flights together on Expedia, where bundling can lead to significant savings.
How much is the nightly rate at a San Francisco hotel?
Hotel prices in San Francisco often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

Explore a world of travel with Expedia